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23 Jun 2016
Blood Test Predicts Personalized Depression Treatment
24 May 2016
Innovative Gene Testing Technology Finds Cancer Risks
28 Apr 2016
Galectin-3 And Cardiac Troponins Reference Values Determined
12 Feb 2016
Prognostic Biomarker Found for Colon Cancer Patients
24 Nov 2015
Low Vitamin D Levels May Harm Heart Health
14 Nov 2015
Diabetic Risk in Obesity Delineated by Metabolic Status
19 Aug 2015
Successful Transport of Blood Samples with Small Drones
16 Feb 2015
Potential Biomarkers for High-Risk Colon Cancer Discovered
07 Jan 2015
Genome Analysis Study to Aid Diagnosis of Rare Developmental Disorders
05 Sep 2014
US FDA Approves Noninvasive DNA Colorectal Cancer Screening Test
29 May 2014
Lab-On-Chip Created for Malaria Diagnosis
29 Mar 2014
New Microarray-Based Glycoprofiling Test Diagnoses Ovarian Cancer
04 Mar 2014
Circulating Tumor DNA a Sensitive and Specific Cancer Biomarker
24 Jan 2014
Biomarker Improves Diagnosis of Esophageal Cancer
20 Jan 2014
Molecular Diagnostics Optimized for Breast Cancer Tissue Samples
15 Jan 2014
Cervical Cancer Genomic Study Completed
07 Jan 2014
Analysis of Saliva DNA Suggested for Screening Stroke-Linked Mutation
25 Nov 2013
Bacterial Toxin Sets the Course for Infection
20 Nov 2013
Blood Levels of Genetic Material Predict Thyroid Cancer Recurrence
07 Nov 2013
Bacterium Evaluated as Potential Multiple Sclerosis Trigger
01 Nov 2013
Gout Detected from a Simple Blood Sample
19 Oct 2013
Identified Genes Associated with Unhealthy Liver Function
17 Oct 2013
Urinary Biomarker Assessed for Diabetes Mellitus
05 Oct 2013
Biomarker Identified for Smoker’s Lung Cancer
03 Oct 2013
Gene-Expression Biomarker Predicts Risk of Breast Cancer Recurrence
30 Sep 2013
Molecular Method Detects Colon Cancer Earlier
27 Sep 2013
Solid Tumor Marker Diagnostic Test Receives CE Certification
21 Sep 2013
Enteric Pathogens Expand After Antibiotic Treatment
20 Sep 2013
Risk Factors Predict Outcomes for Children with Hypertrophic Cardiomyopathy
18 Sep 2013
Prenatal Hormone Levels Linked to Gestational Diabetes Risk
12 Sep 2013
Persistent Urinary Albumin May Indicate Risk for Cognitive Decline in Type II Diabetics
09 Sep 2013
Oncogenic Mutations Found in Cervical Cancer
03 Sep 2013
Genetic Mutation Linked to Thoracic Aortic Disease
30 Aug 2013
Genetic Clues to Epilepsy Discovered
29 Aug 2013
Screening Test Detects Early Onset Preeclampsia
26 Aug 2013
High Blood Glucose Levels Linked to Dementia
19 Aug 2013
Cancer Biomarkers Detected Directly In Blood
29 Jul 2013
Coagulation Assays Diagnose Discrepant Mild Hemophilia
24 Jul 2013
Potential Blood Test for Heart Disease Discovered
22 Jul 2013
Immunological Tests Are Superior for Colon Cancer Screening
05 Jul 2013
Blood Test Predicts Diabetes Mellitus Type 1 Risk
03 Jul 2013
Serum Biomarker Determined for Colorectal Cancer
29 Jun 2013
Pathogen Molecular Diagnostics Evaluated for Routine Use
26 Jun 2013
DNA Blood Test Increases Targeted Treatment Access
14 Jun 2013
Gene Discovered for Congenital Heart Disease
06 Jun 2013
Biomarkers Discovered for Inflammatory Bowel Disease
31 May 2013
Platelet Testing Helps Patients at Risk of Bleeding
24 May 2013
Higher Blood Lead Levels Lower IQ
22 May 2013
Test to Aid Doctors Diagnose and Monitor Diabetes
20 May 2013
Yiannoukas Medical Laboratories has been Accredited
17 May 2013
Gut Bacteria Byproduct Predicts Heart Attack
11 May 2013
Urine Tests Improve Detection of Liver Cancer and Cholangiocarcinoma
09 May 2013
Novel Biomarker Diagnoses Acute Heart Failure
29 Apr 2013
Tests Provide Fuller Picture of Cancer Mutations
19 Apr 2013
Serum Metabolomics Diagnoses Pancreatic Cancer
17 Apr 2013
Biomarkers Diagnose Bacteremia in Bone and Joint Infections
16 Apr 2013
Urine-Based Human Papillomavirus Test Launched
10 Apr 2013
DNA Test Detects Mutations Across Multiple Genes
05 Apr 2013
Blood Test Tracks Response to Cancer Treatment
04 Apr 2013
Prostate Cancer Test Closer to Clinical Trial
03 Apr 2013
Blood Protein Detects Higher Risk of Cardiovascular Event
27 Mar 2013
Blood Test Reveals Extent of Brain Damage
23 Mar 2013
Breath Test Detects and Diagnoses Stomach Cancer
22 Mar 2013
Multiplex Genotyping Developed for Rare Blood Types
19 Mar 2013
Nanochip Device Identifies Melanoma Cells
15 Mar 2013
Lab-on-a-Chip Promises Biochemical Diagnostics
08 Mar 2013
Biological Marker Predicts Susceptibility to Common Cold
06 Mar 2013
Fungi Identified in Asthma Patients’ Lungs
05 Mar 2013
Genetic Susceptibility Loci Identified for Colorectal Tumors
02 Mar 2013
Genetic Root Identified For Early-Onset Prostate Cancer
27 Feb 2013
Molecular Blood Test Detects Colorectal Cancer
25 Feb 2013
Vigorous Mixing May Effect Blood Results
22 Feb 2013
Genetic Test Reveals Predisposition for Abnormal Blood Clotting
20 Feb 2013
Serological Assay Assessed for Dyspepsia Patients
16 Feb 2013
Genetic Test Identifies Small but Deadly Lung Cancers
15 Feb 2013
Blood Test Accurately Diagnoses Depression
14 Feb 2013
Blood Calcium Levels Linked to Ovarian Cancer
12 Feb 2013
Leukocyte Ratio Predicts Ulcerative Colitis Severity
09 Feb 2013
Increasing Antigen Levels Predicts Aggressive Prostate Cancer
08 Feb 2013
Test Predicts Harmful Breast Cancer Mutations
07 Feb 2013
2,5 Μήνες Αναμονή για Αναλύσεις Θυρεοειδούς στα Κρατικά Κλινικά Εργαστήρια
06 Feb 2013
Novel Immunoassay Evaluated for Cardiac Troponin
05 Feb 2013
Microscopic Hematuria an Unreliable Indicator of Bladder Cancer
04 Feb 2013
Blood Test Predicts Breast Cancer Recurrence
02 Feb 2013
Heliprobe® System-Accurate diagnosis of Helicobacter Pylori
01 Feb 2013
Enzyme Discovered May Lead to Better TB Test
31 Jan 2013
Selective Use of D-Dimer Test for Deep Vein Thrombosis
30 Jan 2013
Rapid-Response Chemiluminescent Analyzer Launched for Clinical Laboratories
28 Jan 2013
Ovarian, Endometrial Cancers Detected Using Cervical Fluid
26 Jan 2013
Mass Spectrometry Identifies Bacterial and Yeast Isolates
24 Jan 2013
Genetic Mystery of Behçet''s Disease Revealed
23 Jan 2013
Urinary Enzyme Levels Correlate with Prediabetic Plasma Glucose
22 Jan 2013
Prostate Cancer Genetic Tests Predicts Prognosis
21 Jan 2013
Enzyme Linked to Aggressive Prostate Cancer
19 Jan 2013
Technique Catalogs Lymphoma-Linked Genetic Variations
17 Jan 2013
Modular Laboratory Workflow Platform Placements Exceed Expectations
16 Jan 2013
Cell Block Technique Detects Low Frequency Abnormal Cells
15 Jan 2013
Real Time PCR Assays Compared for Viral Quantification
11 Jan 2013
Genetic Defect That Causes Fragile X Disorder Is Widespread
10 Jan 2013
Spectroscopy Aids Breast Cancer Diagnosis
08 Jan 2013
Coagulation Test Correlates Protein Concentration for Plasma Cell Dyscrasia
06 Jan 2013
Genetic Mutations Identified for Cowden Syndrome
03 Jan 2013
Biomarker Identified for Multiple Myeloma
02 Jan 2013
Metabolism Measurements Predict Progress of Alzheimer’s disease
29 Dec 2012
Multifold Genes Identified for Crohn''s Disease
28 Dec 2012
Immune Protein Levels Predict Hodgkin Disease Risk
27 Dec 2012
Rapid Influenza Diagnostic Tests Evaluated
19 Dec 2012
Sensor Detects Individual Particles in Blood Sample
14 Dec 2012
Procalcitonin Assay to Be Available to Broader Patient Base
13 Dec 2012
Serum Cortisol Predicts Death and Critical Disease
12 Dec 2012
Cancer Detected Using Blood Test and Gene Sequencing
11 Dec 2012
Molecular Diagnostic Test Detects Transrenal Cancer Mutations
10 Dec 2012
Protein Test Predicts Progression in Lou Gehrig''s Disease
06 Dec 2012
Cervical Cancer Test Can Improve Early Detection
04 Dec 2012
Early Markers Detected For Epstein Barr Virus
01 Dec 2012
Alzheimer''s Linked to Rare Gene Mutation
29 Nov 2012
Inflammation Marker Linked to Increased Cancer Death Risk
28 Nov 2012
Sperm DNA Test Diagnoses Idiopathic Infertility
28 Nov 2012
Blood Hormone Levels Predict Long-Term Breast Cancer Risk
26 Nov 2012
Simple Blood Test Assesses Colon Cancer Risk
22 Nov 2012
Circulating Blood Factor Linked to Kidney Failure
20 Nov 2012
Blood Marker Reveals Diabetes Risk in Advance
17 Nov 2012
Blood Test Predicts Survival in Merkel Cell Carcinoma
16 Nov 2012
Biomarkers Identified for Differentiating Alzheimer’s Disease
15 Nov 2012
Androgen Receptor May Impact Prostate Cancer Test
13 Nov 2012
Novel Genes Identified for Rare Uterine Cancer
11 Nov 2012
Specific Bacterial Species May Initiate Crohn’s Disease
09 Nov 2012
Blood Marker Linked to Pancreatic Cancer
08 Nov 2012
Molecular Blood Test Diagnoses Herpes Simplex Virus Infection
07 Nov 2012
Shiga Toxin-Producing E. coli Directly Detected from Stool
05 Nov 2012
Ultrasensitive Sensor Detects Early Stages of Diseases
01 Nov 2012
Noninvasive Test Developed for Colorectal Cancer
31 Oct 2012
Glutamate a Promising New Biomarker for Prostate Cancer Aggressiveness
29 Oct 2012
Serological Assays Assessed for Q Fever
27 Oct 2012
Gene Test Detects Early Mouth Cancer
26 Oct 2012
Biomarkers Identified for Type 2 Diabetes
25 Oct 2012
A Single-Molecule Digital Immunoassay Identifies HIV in Blood
24 Oct 2012
Premature Birth Predicted by Immunoassay
23 Oct 2012
Anti-Cancer Drug Closer to Marketplace
22 Oct 2012
Urine Test Predicts Risk of Bone Fracture
19 Oct 2012
High Glucose Levels Predict Mortality in Pneumonia
18 Oct 2012
Gene Biomarker May Predict Sudden Heart Failure
17 Oct 2012
Lactate Concentrations Evaluated In Suspected Infections
17 Oct 2012
Gene Activity in Blood Identifies Aggressive Prostate Cancers
16 Oct 2012
Potential Biomarkers Identified for Ulcerative Colitis
15 Oct 2012
Tests Combined for Early Diagnosis of Liver Disease
13 Oct 2012
Biomarker Found for Parkinson’s Disease
12 Oct 2012
Blood Test Detects Early Stages of Cancer
12 Oct 2012
Blood Type May Affect Heart Disease Risk
10 Oct 2012
New Blood Test to Spot Breast Cancer Early
02 Oct 2012
The very first EVER App for Medical Laboratories
29 Sep 2012
Our New Laboratory 2012
27 Sep 2012
Welcome to Our New Website
27 Sep 2012
Soon everyone will be talking about our new innovation. LAUNCH OCTOBER 2012
Cervical Cancer Genomic Study Completed
15 Jan 2014
 
 
A comprehensive genomic analysis of cervical cancer in two patient populations has been completed and recurrent genetic mutations have been identified not previously found in cervical cancer.

Cervical cancer is the second most common cancer in women and is responsible for approximately 10% of cancer deaths in women, particularly in developing countries where screening methods are not readily accessible and almost all cases of the disease are caused by exposure to human papillomavirus (HPV). 

An international team of scientists and led by those from the Broad Institute (Cambridge, MA, USA) performed whole exome sequencing, which examines the genetic code in the protein-coding regions of the genome, on samples from 115 cervical cancer patients from Norway and Mexico. Genomic DNA and ribonucleic acid (RNA) were extracted from tumors found by frozen section investigations to have greater than 40% malignant epithelial cell component. 

DNA from 115 tumor-normal paired samples was subjected to Sure-Select Human All Exon v2.0 based hybrid selection (Agilent; Santa Clara, CA, USA) followed by exome library construction for sequencing (Illumina; San Diego, CA, USA), and 14 pairs for whole genome library construction. Complementary DNA (cDNA) from 79 samples was subjected to transcriptome library construction, according to standard methods.

The study identified 13 mutations that occurred frequently enough across the samples to be considered significant in cervical cancer. Eight of these mutations had not been linked to the disease previously, and two had not previously been seen in any cancer type. Among the most notable findings were somatic point mutations in the V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog gene (ERBB2), which was found in a small, but significant subset of the tumors. Mutations in this gene had not been previously been linked to cervical cancer, but it is a known oncogene common in breast cancer. The team also identified a novel mutation in the mitogen-activated protein kinase 1 (MAPK1) gene and another key finding was the prevalence of mutations in genes affecting the immune system. 

Hugo Alberto Barrera Saldaña, PhD, a professor of biochemistry and coauthor of the study said, “The outstanding findings of our successful collaborative international research is giving us, here in Mexico, very powerful arguments in favor of the benefit of speeding up the adoption of molecular methods for screening HPV, followed by colposcopy to detect cancer at its earliest phases when it is curable; not to mention the possibility of new targeted therapies that our discoveries open up.” The study was published on December 25, 2103, in the journal Nature.
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Address:Aglantzia, Lakatamia, Dometios, Strovolos, Latsia, Makedonitissa
Pancyprian Number: 77 77 13 10
From Abroad:+357 22 204 900
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Thursday and Saturday: 07:30 to 13:00
Sunday: Closed
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Address:Astromeritis
Pancyprian Number: 77 77 13 10
From Abroad:+357 22 204 900
Monday, Tuesday, Wednesday, Friday: 06:30 to 12:30,
15:30 to 18:00
Thursday: 06:30 to 13:00
Saturday: 07:30 to 13:00
Sunday: Closed
Book an appointment